Monopoli is a town on the Adriatic Sea, in southern Italy. It’s known for the Baroque Monopoli Cathedral, featuring a tall bell tower. In its crypt is an archaeological museum with sculptures and ancient tombs. On a promontory to the north, the 16th-century Castle of Carlo V has a huge stone portal. Nearby is the frescoed Palmieri Palace, built by a wealthy local family in the late 1700s.